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No expiration date on COVID-19 vaccine label... STS abbreviation results in a close call...
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No expiration date on COVID-19 vaccine label... STS abbreviation results in a close call...
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COVID-19 vaccine package concerns... Potassium chloride for injection concentrate 250 mL bags reaching organizations... Pharmacists can now prescribe Paxlovid but should be aware of error risks
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Paxlovid drug interaction... Eprontia oral solution concentration conversion... Different concentrations of oral liquid Baclofen
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The article presents medication errors received through the Institute for Safe Medication Practices (ISMP) Medication Errors Reporting Program. These include a potential safety issue after a hospital pharmacist switched from the usual supply of lipid injectable emulsion to Baxter's Clinolipid 20%, the accidental dilution of the new prediluted form of the COVID-19 vaccine from Pfizer-BioN-Tech, and intravenous (I.V.) tubing spikes falling out of Douglas Medical Products (DMP) I.V. bags.
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Age-related COVID-19 vaccine mix-ups... Onpattro requires a 0.45-micron filter for preparation... Prasugrel unavailable in unit-dose packaging
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This section offers news briefs about medication errors as of November 2021. The pharmaceutical company Regeneron has developed a new temporary alternative packaging for casirivimab and imdevimab (REGEN-COV). The National Health Service in England has released a National Patient Safety Alert calling for the elimination of bottles of liquid, high-strength phenol.
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The article offers updates on medication error issues in the U.S. as of July 2021. Topics covered include education of clinicians about the benefits of reporting errors involving nutrition support therapy and associated devices, a linear bar code required by the U.S. Food and Drug Administration Barcode Rule that encodes the product's National Drug Code number, and confusion over measuring liquid medication doses using the syringe scale printed on Covidien's Monoject 3-mL enteral syringes.
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The article offers medical news briefs as of April 2021. A free COVID-19 vaccine handling toolkit for healthcare professionals was published by U.S. Pharmacopeia (USP). Hikma failed to include its warning on disposal on the bottle or outer carton of its Rufinamide oral suspension generic antiepileptic drug. Also cited is the error in the labeling for the Piqray (alpelisib) kinase inhibitor drug.
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The article discusses medication issues, particularly on the use of the bamlanivimab monoclonal antibody from Eli Lilly, heparin and hypertonic sodium chloride. Also cited are the confusing information on the administration rate of bamlanivimab, and the high possibility of error on the use of heparin and sodium chloride due to their similar packaging.
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The COVID-19 pandemic increased the demand for neuromuscular blocking agents for critically ill patients requiring mechanical ventilation, leading to a shortage of the neuromuscular blocking agents vecuronium and rocuronium. To assure continued availability of these two critically important drugs, the FDA is permitting the temporary manufacture of these drugs without the vial cap (seal) incorporating the warning, "Paralyzing Agent," normally required by USP and the FDA. Supply constraints prevented manufacturers from obtaining the products with the usual warning statements on the vial cap in time to address the shortage. This temporary situation has obvious safety implications because the absence of warning may make the vials look more like other medications with similar size vials and cap colors.
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An ICU hospitalist decided to order Actemra (tocilizumab) to treat a patient with confirmed COVID-19 and evidence of cytokine release syndrome. An interleukin-6 receptor antagonist, this drug is approved to treat adults and children age 2 and older with chimeric antigen receptor T cell-induced severe or life-threatening cytokine release syndrome. The drug, which has an anti-inflammatory effect, was undergoing a clinical trial for patients with COVID-19 and pneumonia, but it is not FDA-approved for this purpose.